Quinolones versus macrolides in the treatment of legionellosis: a systematic review and meta-analysis

201449 citationsReviewbronze Open Access

Authors

Charles Burdet · Université Paris Cité

R. Lepeule · Hôpital Beaujon

Xavier Duval · Clinical Investigation Center Plurithematic Tours

Marion Caséris · Assistance Publique – Hôpitaux de Paris

C. Rioux · Centre d'Immunologie et des Maladies Infectieuses

Jean‐Christophe Lucet · Infection, Anti-microbiens, Modélisation, Evolution

Yazdan Yazdanpanah

Abstract

Few clinical data on legionellosis treatment are available. This first meta-analysis showed a trend toward a lower mortality rate and a significant decrease in length of hospital stay among patients receiving quinolones. These results must be confirmed by a randomized controlled trial.

Topics & Keywords

Legionella and Acanthamoeba research Antifungal resistance and susceptibility Neutrophil, Myeloperoxidase and Oxidative Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Antimicrobial Chemotherapy

Volume 69, Issue 9, pp. 2354-2360

DOI: 10.1093/jac/dku159

Field-Weighted Citation Impact: 3.85