Autologous Mesenchymal Stromal Cells and Kidney Transplantation

2010305 citationsJournal Articlegreen Open Access

Authors

Norberto Perico · Mario Negri Institute for Pharmacological Research

Federica Casiraghi · University of Bergamo

Martino Introna

Eliana Gotti · University of Bergamo

Marta Todeschini · University of Bergamo

Regiane Aparecida Cavinato · Mario Negri Institute for Pharmacological Research

Chiara Capelli

Alessandro Rambaldi

Abstract

Findings from this study in the two patients show that MSC infusion in kidney transplant recipients is feasible, allows enlargement of Treg in the peripheral blood, and controls memory CD8+ T cell function. Future clinical trials with MSCs to look with the greatest care for unwanted side effects is advised.

Topics & Keywords

Mesenchymal stem cell research Extracellular vesicles in disease Hematopoietic Stem Cell Transplantation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Journal of the American Society of Nephrology

Volume 6, Issue 2, pp. 412-422

DOI: 10.2215/cjn.04950610

Field-Weighted Citation Impact: 9.99