Validation of Contrast-Enhanced Magnetic Resonance Imaging to Monitor Regenerative Efficacy After Cell Therapy in a Porcine Model of Convalescent Myocardial Infarction

2013110 citationsJournal Articlebronze Open Access

Authors

Konstantinos Malliaras · Capricor Therapeutics (United States)

Rachel Smith · Capricor Therapeutics (United States)

Hideaki Kanazawa · Gift of Life Michigan

Kristine Yee · Capricor Therapeutics (United States)

Jeffrey Seinfeld · Capricor Therapeutics (United States)

Eleni Tseliou · Capricor Therapeutics (United States)

James Dawkins

Abstract

Contrast-enhanced MRI accurately measures scarred and viable myocardium after cell therapy in a porcine model of convalescent MI. MRI represents a useful tool for assessing dynamic changes in the infarct and monitoring regenerative efficacy.

Topics & Keywords

Tissue Engineering and Regenerative Medicine Mesenchymal stem cell research Cardiac Structural Anomalies and Repair

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 128, Issue 25, pp. 2764-2775

DOI: 10.1161/circulationaha.113.002863

Field-Weighted Citation Impact: 13.95