Prediction of Survival in Multiple Myeloma Based on Gene Expression Profiles Reveals Cell Cycle and Chromosomal Instability Signatures in High-Risk Patients and Hyperdiploid Signatures in Low-Risk Patients: A Study of the Intergroupe Francophone du Myélome

2008368 citationsJournal Article

Authors

Olivier Decaux · Nantes Université

Laurence Lodé · Nantes Université

Florence Magrangeas · Nantes Université

Catherine Guérin‐Charbonnel · Nantes Université

Wilfried Gouraud · Nantes Université

Pascal Jézéquel · Nantes Université

Michel Attal ·

Abstract

Gene expression-based survival prediction and molecular features associated with high-risk patients may be useful for developing prognostic markers and may provide basis to treat these patients with new targeted antimitotics.

Topics & Keywords

Multiple Myeloma Research and Treatments Cancer Mechanisms and Therapy 14-3-3 protein interactions

Publication Details

Published in: Journal of Clinical Oncology

Volume 26, Issue 29, pp. 4798-4805

DOI: 10.1200/jco.2007.13.8545

Field-Weighted Citation Impact: 10.51

Command Palette

Prediction of Survival in Multiple Myeloma Based on Gene Expression Profiles Reveals Cell Cycle and Chromosomal Instability Signatures in High-Risk Patients and Hyperdiploid Signatures in Low-Risk Patients: A Study of the Intergroupe Francophone du Myélome

Authors

Abstract

Topics & Keywords

Publication Details