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Biosensing has been one of the hottest topic attracting scientific minds since long back. It is so as biological entities are very complex and are directly associated with the existence of a healthy environment. The design of biosensors also has witnessed significant changes in the recent past. Biosensors for applications as diverse as food quality estimation, environmental monitoring, and diagnosis of clinical and metabolic complications have come to the fore. Nanotechnology has bestowed some highly exciting ingredients for the improvement of sensing phenomenon. The use of diverse nanomaterials ranging from nanoparticles, nanotubes, nanorods, and nanowires has enabled faster detection and its reproducibility in a much better way. The unique properties of nanomaterials such as high electrical conductivity, better shock bearing ability, and the sensitive responses such as piezoelectric and versatile color based detection mechanisms are only the results of congregation of nanomaterial properties. This paper highlights the different types of biosensors based on different types of nanomaterials and their developmental and implicational aspects.