Multivariate miRNA signatures as biomarkers for non-ischaemic systolic heart failure

2013113 citationsJournal Articlebronze Open Access

Authors

Britta Vogel · Heidelberg University

Andreas Keller · Hummingbird Diagnostics (Germany)

Karen Frese · Heidelberg University

Petra Leidinger · Saarland University

Farbod Sedaghat‐Hamedani · Heidelberg University

Elham Kayvanpour · Heidelberg University

Wanda Kloos ·

Abstract

Our data further denote that miRNAs are potential biomarkers for systolic heart failure. Since their detection levels in whole blood are also related to the degree of left ventricular dysfunction, they may serve as objective molecular tools to assess disease severity and prognosis.

Topics & Keywords

MicroRNA in disease regulation Circular RNAs in diseases Cancer-related molecular mechanisms research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European Heart Journal

Volume 34, Issue 36, pp. 2812-2823

DOI: 10.1093/eurheartj/eht256

Field-Weighted Citation Impact: 5.48