Estimation and assessment of raw copy numbers at the single locus level

2008145 citationsJournal Articlebronze Open Access

Authors

Henrik Bengtsson · Walter and Eliza Hall Institute of Medical Research

Rafael A. Irizarry · Walter and Eliza Hall Institute of Medical Research

Benilton S. Carvalho · Johns Hopkins University

Terence P. Speed · Johns Hopkins University

Abstract

The proposed method is available as part of an open-source R package named aroma.affymetrix. Because it is a bounded-memory algorithm, any number of arrays can be analyzed.

Topics & Keywords

Genomic variations and chromosomal abnormalities Gene expression and cancer classification Molecular Biology Techniques and Applications

UN Sustainable Development Goals

Partnerships for the goals

Publication Details

Published in: Bioinformatics

Volume 24, Issue 6, pp. 759-767

DOI: 10.1093/bioinformatics/btn016

Field-Weighted Citation Impact: 12.47