Associations of 25(OH) and 1,25(OH)<sub>2</sub>Vitamin D With Long-Term Outcomes in Stable Renal Transplant Recipients

201475 citationsJournal Articlebronze Open Access

Authors

Charlotte A. te Velde‐Keyzer · University of Groningen

Ineke J. Riphagen · University of Groningen

Michel M. Joosten · University Medical Center Groningen

Gerjan Navis · University of Groningen

Anneke C. Muller Kobold · University of Groningen

Ido P. Kema · University Medical Center Groningen

Stephan J. L. Bakker

Abstract

Low 25(OH)D is independently associated with an increased risk of all-cause mortality and 25(OH)D <12 ng/ml with a rapid eGFR decline in stable RTR. The association of low 1,25(OH)2D with mortality or graft failure depends on renal function. These results should encourage randomised controlled trials evaluating the effect of vitamin D supplementation after kidney transplantation.

Topics & Keywords

Vitamin D Research Studies Pharmacological Effects and Toxicity Studies Pregnancy and Medication Impact

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 100, Issue 1, pp. 81-89

DOI: 10.1210/jc.2014-3012

Field-Weighted Citation Impact: 6.12