Methylation of HPV18, HPV31, and HPV45 Genomes and Cervical Intraepithelial Neoplasia Grade 3

2012164 citationsJournal Article

Authors

Nicolas Wentzensen · Kaiser Permanente

Chang Sun · Yunnan University

Arpita Ghosh · National Institutes of Health

Walter Kinney · Albert Einstein College of Medicine

Lisa Mirabello · Albert Einstein College of Medicine

Sholom Wacholder · Kaiser Permanente

Ruth Shaber ·

Abstract

Carcinogenic HPV DNA methylation indicates transforming HPV infections. Our findings show that methylation of carcinogenic HPV types is a general phenomenon that warrants development of diagnostic assays.

Topics & Keywords

Cervical Cancer and HPV Research Reproductive tract infections research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JNCI Journal of the National Cancer Institute

Volume 104, Issue 22, pp. 1738-1749

DOI: 10.1093/jnci/djs425

Field-Weighted Citation Impact: 8.63