MicroRNA-26a negatively regulates toll-like receptor 3 expression of rat macrophages and ameliorates pristane induced arthritis in rats

2014101 citationsJournal Articlegold Open Access

Authors

Congshan Jiang · Xi'an Jiaotong University

Wenhua Zhu · Xi'an Jiaotong University

Jing Xu · Xi'an Jiaotong University

Bo Wang · Xi'an Jiaotong University

Weikun Hou · Xi'an Honghui Hospital

Rui Zhang · Xi'an Jiaotong University

Nannan Zhong ·

Abstract

MiR-26a negatively regulates TLR3 signaling via targeting of TLR3 itself in rat macrophages, and this finding provides a novel insight into abnormal TLR3 overexpression during experimental arthritis.

Topics & Keywords

MicroRNA in disease regulation Cancer-related molecular mechanisms research Circular RNAs in diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Arthritis Research & Therapy

Volume 16, Issue 1, pp. R9-R9

DOI: 10.1186/ar4435

Field-Weighted Citation Impact: 2.77