Apparently conclusive meta-analyses may be inconclusive—Trial sequential analysis adjustment of random error risk due to repetitive testing of accumulating data in apparently conclusive neonatal meta-analyses

2008948 citationsJournal Articlebronze Open Access

Authors

Kristian Thorlund · Copenhagen University Hospital

Jørn Wetterslev · Copenhagen University Hospital

Abstract

Many apparently conclusive Cochrane neonatal meta-analyses may become inconclusive when the statistical analyses take into account the risk of random error due to repetitive testing.

Topics & Keywords

Meta-analysis and systematic reviews Hemodynamic Monitoring and Therapy Statistical Methods in Clinical Trials

Publication Details

Published in: International Journal of Epidemiology

Volume 38, Issue 1, pp. 287-298

DOI: 10.1093/ije/dyn188

Field-Weighted Citation Impact: 17.49

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Apparently conclusive meta-analyses may be inconclusive—Trial sequential analysis adjustment of random error risk due to repetitive testing of accumulating data in apparently conclusive neonatal meta-analyses

Authors

Abstract

Topics & Keywords

Publication Details