Diuretic Strategies in Patients with Acute Decompensated Heart Failure

20111,655 citationsJournal Articlebronze Open Access

Authors

G. Michael Felker · Duke University

Kerry L. Lee · Clinical Research Institute

David A. Bull · University of Utah

Margaret M. Redfield · Mayo Clinic in Arizona

Lynne W. Stevenson · Brigham and Women's Hospital

Steven R. Goldsmith · University of Minnesota System

Martin M. LeWinter

Abstract

Among patients with acute decompensated heart failure, there were no significant differences in patients' global assessment of symptoms or in the change in renal function when diuretic therapy was administered by bolus as compared with continuous infusion or at a high dose as compared with a low dose. (Funded by the National Heart, Lung, and Blood Institute; ClinicalTrials.gov number, NCT00577135.).

Topics & Keywords

Heart Failure Treatment and Management Electrolyte and hormonal disorders Renal function and acid-base balance

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 364, Issue 9, pp. 797-805

DOI: 10.1056/nejmoa1005419

Field-Weighted Citation Impact: 77.19