The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression

2014308 citationsJournal Articlegold Open Access

Authors

Christopher Benner · Salk Institute for Biological Studies

Talitha van der Meulen · Salk Institute for Biological Studies

Elena L. Cáceres · Salk Institute for Biological Studies

Kristof Tigyi · Salk Institute for Biological Studies

Cynthia J. Donaldson · Salk Institute for Biological Studies

Mark O. Huising · University of California, Davis

Abstract

The comprehensive mouse alpha and beta cell transcriptomes complemented by the comparison of the global (dis)similarities between mouse and human beta cells represent invaluable resources to boost the accuracy by which rodent models offer guidance in finding cures for human diabetes.

Topics & Keywords

Pancreatic function and diabetes Metabolism, Diabetes, and Cancer Diabetes and associated disorders

Publication Details

Published in: BMC Genomics

Volume 15, Issue 1, pp. 620-620

DOI: 10.1186/1471-2164-15-620

Field-Weighted Citation Impact: 24.93

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The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression

Authors

Abstract

Topics & Keywords

Publication Details