IL-23 and Th17 Cells Enhance Th2-Cell–mediated Eosinophilic Airway Inflammation in Mice

2008440 citationsJournal Article

Authors

Hidefumi Wakashin · Chiba University Hospital

Koichi Hirose

Yoshiro Maezawa · Chiba University Hospital

Shin‐ichiro Kagami · Chiba University Hospital

Akira Suto · Chiba University Hospital

Norihiko Watanabe · Chiba University Hospital

Yasushi Saito

Masahiko Hatano

Abstract

IL-23 and Th17 cells not only induce Th17-cell-mediated neutrophilic airway inflammation but also up-regulate Th2-cell-mediated eosinophilic airway inflammation.

Topics & Keywords

Asthma and respiratory diseases Pediatric health and respiratory diseases Psoriasis: Treatment and Pathogenesis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Respiratory and Critical Care Medicine

Volume 178, Issue 10, pp. 1023-1032

DOI: 10.1164/rccm.200801-086oc

Field-Weighted Citation Impact: 16.93