Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages

20011,278 citationsJournal Article

Authors

Noriyuki Ouchi · Otsuka (Japan)

Shinji Kihara · Otsuka (Japan)

Yukio Arita · Otsuka (Japan)

Makoto Nishida · Otsuka (Japan)

Akifumi Matsuyama · Otsuka (Japan)

Yoshihisa Okamoto · Otsuka (Japan)

Masato Ishigami · Otsuka (Japan)

Abstract

The adipocyte-derived plasma protein adiponectin suppressed macrophage-to-foam cell transformation, suggesting that adiponectin may act as a modulator for macrophage-to-foam cell transformation.

Topics & Keywords

Adipokines, Inflammation, and Metabolic Diseases Adipose Tissue and Metabolism Blood properties and coagulation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 103, Issue 8, pp. 1057-1063

DOI: 10.1161/01.cir.103.8.1057

Field-Weighted Citation Impact: 37.46