V(D)J Recombination: Molecular Biology and Regulation

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Authors

David G. Schatz · Howard Hughes Medical Institute

Marjorie A. Oettinger · Harvard University Press

Mark S. Schlissel · Johns Hopkins University

Abstract

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More

Topics & Keywords

Immune Cell Function and Interaction T-cell and B-cell Immunology Cytomegalovirus and herpesvirus research

Publication Details

Published in: Annual Review of Immunology

Volume 10, Issue 1, pp. 359-383

DOI: 10.1146/annurev.iy.10.040192.002043

Field-Weighted Citation Impact: 17.23

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V(D)J Recombination: Molecular Biology and Regulation

Authors

Abstract

Topics & Keywords

Publication Details