Filaggrin Mutations Associated with Skin and Allergic Diseases

20111,191 citationsReview

Authors

Donald Y.M. Leung · National Jewish Health

Abstract

Mutations in the filaggrin gene are associated with a broad range of skin and allergic diseases. The biology of this molecule and the role of mutations in its altered function offer new insights into a range of conditions not previously thought to be related to one another.

Topics & Keywords

Dermatology and Skin Diseases Allergic Rhinitis and Sensitization Food Allergy and Anaphylaxis Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 365, Issue 14, pp. 1315-1327

DOI: 10.1056/nejmra1011040

Field-Weighted Citation Impact: 85.62