Apple polyphenol extracts prevent damage to human gastric epithelial cells in vitro and to rat gastric mucosa in vivo

2005178 citationsJournal Articlebronze Open Access

Authors

Giulia Graziani

G D’Argenio

C Tuccillo · Centro Interuniversitario di Ricerca sui Peptidi Bioattivi

C Loguercio · Centro Interuniversitario di Ricerca sui Peptidi Bioattivi

A Ritieni · University of Naples Federico II

F Morisco · University of Naples Federico II

C Del Vecchio Blanco · Centro Interuniversitario di Ricerca sui Peptidi Bioattivi

V Fogliano · University of Naples Federico II

Abstract

Apple extracts prevent exogenous damage to human gastric epithelial cells in vitro and to the rat gastric mucosa in vivo. This effect seems to be associated with the antioxidant activity of apple phenolic compounds. A diet rich in apple antioxidants might exert a beneficial effect in the prevention of gastric diseases related to generation of reactive oxygen species.

Topics & Keywords

Phytochemicals and Antioxidant Activities Cynara cardunculus studies Microbial Metabolites in Food Biotechnology

Publication Details

Published in: Gut

Volume 54, Issue 2, pp. 193-200

DOI: 10.1136/gut.2004.046292

Field-Weighted Citation Impact: 2.68

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Apple polyphenol extracts prevent damage to human gastric epithelial cells in vitro and to rat gastric mucosa in vivo

Authors

Abstract

Topics & Keywords

Publication Details