MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia

20121,261 citationsJournal Articlebronze Open Access

Authors

Steven P. Treon · Dana-Farber Cancer Institute

Lian Xu · Harvard University

Guang Yang · Dana-Farber Cancer Institute

Yangsheng Zhou · Harvard University

Xia Liu · Dana-Farber Cancer Institute

Yang Cao · Dana-Farber Cancer Institute

Patricia Sheehy ·

Abstract

MYD88 L265P is a commonly recurring mutation in patients with Waldenström's macroglobulinemia that can be useful in differentiating Waldenström's macroglobulinemia and non-IgM LPL from B-cell disorders that have some of the same features. (Funded by the Peter and Helen Bing Foundation and others.).

Topics & Keywords

Chronic Lymphocytic Leukemia Research Lymphoma Diagnosis and Treatment Calcium signaling and nucleotide metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 367, Issue 9, pp. 826-833

DOI: 10.1056/nejmoa1200710

Field-Weighted Citation Impact: 41.87