Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

20132,181 citationsJournal Articlebronze Open Access

Authors

Sarah‐Jane Dawson · University of Cambridge

Dana W.Y. Tsui · National Institute for Health Research

Muhammed Murtaza · Cancer Research UK

Heather Biggs · Addenbrooke's Hospital

Oscar M. Rueda · Addenbrooke's Hospital

Suet‐Feung Chin · Cancer Research UK

Mark Dunning ·

Abstract

This proof-of-concept analysis showed that circulating tumor DNA is an informative, inherently specific, and highly sensitive biomarker of metastatic breast cancer. (Funded by Cancer Research UK and others.).

Topics & Keywords

Cancer Genomics and Diagnostics Cancer Cells and Metastasis Genetic factors in colorectal cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 368, Issue 13, pp. 1199-1209

DOI: 10.1056/nejmoa1213261

Field-Weighted Citation Impact: 72.33