A Shift towards Pro-Inflammatory CD16+ Monocyte Subsets with Preserved Cytokine Production Potential after Kidney Transplantation

201333 citationsJournal Articlegold Open Access

Authors

Elly J. F. Vereyken · Erasmus MC

Marina D. Kraaij · Erasmus MC

Carla C. Baan · Erasmus MC

Farhad Rezaee · University of Groningen

Willem Weimar · Erasmus MC

Kathryn J. Wood · University of Oxford

Pieter J. M. Leenen · Erasmus MC

Abstract

Our data demonstrate a skewed balance towards pro-inflammatory CD16+ monocytes that is present at the time of transplantation and retained for at least 6 months after transplantation. This shift could be one of the important drivers of early post-transplant cellular immunity.

Topics & Keywords

Immune cells in cancer HIV Research and Treatment Reproductive System and Pregnancy

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 8, Issue 7, pp. e70152-e70152

DOI: 10.1371/journal.pone.0070152

Field-Weighted Citation Impact: 1.47