Long-Term Follow-up after Tight Control of Blood Pressure in Type 2 Diabetes

2008768 citationsJournal Articlebronze Open Access

Authors

Rury R. Holman · Oxford Centre for Diabetes, Endocrinology and Metabolism

H. A. W. Neil · Oxford BioMedica (United Kingdom)

David R. Matthews · Oxford Biomedical Research

Abstract

The benefits of previously improved blood-pressure control were not sustained when between-group differences in blood pressure were lost. Early improvement in blood-pressure control in patients with both type 2 diabetes and hypertension was associated with a reduced risk of complications, but it appears that good blood-pressure control must be continued if the benefits are to be maintained. (UKPDS 81; Current Controlled Trials number, ISRCTN75451837.)

Topics & Keywords

Blood Pressure and Hypertension Studies Pharmacology and Obesity Treatment Diabetes, Cardiovascular Risks, and Lipoproteins

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 359, Issue 15, pp. 1565-1576

DOI: 10.1056/nejmoa0806359

Field-Weighted Citation Impact: 50.41