Analgesic Requirements After Major Abdominal Surgery are Associated with <i>OPRM1</i> Gene Polymorphism Genotype and Haplotype

2008140 citationsJournal Article

Authors

Masakazu Hayashida · Tokyo Institute of Psychiatry

Makoto Nagashima · Tokyo Institute of Psychiatry

Yasuo Satoh · Tokyo Institute of Psychiatry

Ryoji Katoh · Tokyo Institute of Psychiatry

M. Tagami · Tokyo Institute of Psychiatry

Soichiro Ide · Tokyo Institute of Psychiatry

Shinya Kasai

Abstract

These results suggest that OPRM1 gene tag SNP genotypes and haplotypes can primarily contribute to prediction of postoperative analgesic requirements in individual patients undergoing major open abdominal surgery.

Topics & Keywords

Pain Management and Opioid Use Pediatric Pain Management Techniques Pain Management and Placebo Effect

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Pharmacogenomics

Volume 9, Issue 11, pp. 1605-1616

DOI: 10.2217/14622416.9.11.1605

Field-Weighted Citation Impact: 8.29