A Multicenter, Randomized Trial of Prophylactic Fluconazole in Preterm Neonates

2007358 citationsJournal Articlebronze Open Access

Authors

Paolo Manzoni · Ospedale Sant'Anna

Ilaria Stolfi · Policlinico Umberto I

Lorenza Pugni · University of Milan

Lidia Decembrino · University Hospital Foundation

Cristiana Magnani

G Vetrano · Fatebenefratelli Hospital

Elisabetta Tridapalli · University of Bologna

Abstract

Prophylactic fluconazole reduces the incidence of colonization and invasive candida infection in neonates weighing less than 1500 g at birth. The benefit of treating candida colonization is unclear. (Current Controlled Trials number, ISRCTN85753869 [controlled-trials.com]).

Topics & Keywords

Neonatal and Maternal Infections Antifungal resistance and susceptibility Infant Development and Preterm Care

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 356, Issue 24, pp. 2483-2495

DOI: 10.1056/nejmoa065733

Field-Weighted Citation Impact: 36.07