Do ethnobotanical and laboratory data predict clinical safety and efficacy of anti-malarial plants?

201192 citationsReviewgold Open Access

Authors

Merlin Willcox · Oxfam

Françoise Benoit‐Vical · Centre National de la Recherche Scientifique

Dennis G. Fowler

Geneviève Bourdy · Université Fédérale de Toulouse Midi-Pyrénées

Gemma Burford · Community College of Philadelphia

Sergio Giani · Aid to Development of Traditional Medicine

Rocky Graziose · Rutgers, The State University of New Jersey

Abstract

The RITAM score (especially the efficacy and safety components) can be used as part of the selection process for prioritising plants for further research as anti-malarial drug candidates. The validation in this study was limited by the very small number of available clinical studies, and the heterogeneity of patients included.

Topics & Keywords

Ethnobotanical and Medicinal Plants Studies Malaria Research and Control Phytochemistry and Bioactivity Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Malaria Journal

Volume 10, Issue S1, pp. S7-S7

DOI: 10.1186/1475-2875-10-s1-s7

Field-Weighted Citation Impact: 8.19