Aging and the Burden of Multimorbidity: Associations With Inflammatory and Anabolic Hormonal Biomarkers

2014235 citationsJournal Articlegreen Open Access

Authors

Elisa Fabbri · Institute on Aging

Yang An · Institute on Aging

Marco Zoli · University of Bologna

Eleanor M. Simonsick · National Institutes of Health

Jack M. Guralnik · University of Maryland, Baltimore

Stefania Bandinelli

Cynthia M. Boyd · Johns Hopkins University

Abstract

Accumulation of chronic diseases accelerates at older ages and in persons with higher baseline levels and steeper increase over time of IL-6. High IL-6 and increase in IL-6 may serve as early warning sign to better target interventions aimed at reducing the burden of multimorbidity.

Topics & Keywords

Chronic Disease Management Strategies Health Systems, Economic Evaluations, Quality of Life Frailty in Older Adults

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journals of Gerontology Series A

Volume 70, Issue 1, pp. 63-70

DOI: 10.1093/gerona/glu127

Field-Weighted Citation Impact: 8.37