Circulating Tumor Cell Analysis in Patients with Progressive Castration-Resistant Prostate Cancer

2007342 citationsJournal Article

Authors

David R. Shaffer · Spanish Oncology Genitourinary Group

Margaret Leversha

Daniel C. Danila · Spanish Oncology Genitourinary Group

Oscar Lin

Rita Gonzalez-Espinoza

Gerald V. Doyle · Eon Corporation (United States)

Abstract

The analysis of cancer-related alterations at the DNA and protein level from CTCs is feasible in a hospital-based clinical laboratory. The alterations observed in EGFR and AR suggest that the methodology may have a role in clinical decision making.

Topics & Keywords

Cancer Cells and Metastasis Cancer Genomics and Diagnostics Prostate Cancer Treatment and Research

UN Sustainable Development Goals

Peace, Justice and strong institutions

Publication Details

Published in: Clinical Cancer Research

Volume 13, Issue 7, pp. 2023-2029

DOI: 10.1158/1078-0432.ccr-06-2701

Field-Weighted Citation Impact: 12.19