Clinicopathologic Features and Long-term Outcomes of NUT Midline Carcinoma

2012401 citationsReviewbronze Open Access

Authors

Daniel E. Bauer · University Hospital of Bern

Chelsey M. Mitchell · University Hospital of Bern

Kelly M. Strait · Harvard University

Christopher S. Lathan · Harvard University

Edward B. Stelow · Azienda Ospedaliero Universitaria Ospedali Riuniti

Sonja Lüer · Dana-Farber Cancer Institute

Somala Muhammed

Abstract

NMC portends a poor prognosis among all squamous cell neoplasms and seems to be frequently unrecognized. The finding that conventional chemotherapy has been inadequate indicates a pressing need for the development of targeted therapeutics. Intensive local therapies such as gross total resection and radiotherapy might be associated with enhanced survival.

Topics & Keywords

Protein Degradation and Inhibitors Ubiquitin and proteasome pathways CAR-T cell therapy research

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Clinical Cancer Research

Volume 18, Issue 20, pp. 5773-5779

DOI: 10.1158/1078-0432.ccr-12-1153

Field-Weighted Citation Impact: 7.65