Intensive versus Conventional Glucose Control in Critically Ill Patients

20095,054 citationsJournal Articlebronze Open Access

Authors

Nice-Sugar Study Investigators · Royal North Shore Hospital

Abstract

In this large, international, randomized trial, we found that intensive glucose control increased mortality among adults in the ICU: a blood glucose target of 180 mg or less per deciliter resulted in lower mortality than did a target of 81 to 108 mg per deciliter. (ClinicalTrials.gov number, NCT00220987.)

Topics & Keywords

Hyperglycemia and glycemic control in critically ill and hospitalized patients Diabetes Management and Research Metabolism, Diabetes, and Cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 360, Issue 13, pp. 1283-1297

DOI: 10.1056/nejmoa0810625

Field-Weighted Citation Impact: 316.47