Relationship Between Regional Cardiac Hyperinnervation and Ventricular Arrhythmia

2000482 citationsJournal Article

Authors

Ji‐Min Cao · University of California, San Diego

Michael C. Fishbein · University of California, San Diego

Jay B. Han · University of California, San Diego

William W. Lai · University of California, Los Angeles

Angela Lai · University of California, Los Angeles

Tsu-Juey Wu · University of California, Los Angeles

L. Czer

Abstract

There is an association between a history of spontaneous ventricular arrhythmia and an increased density of sympathetic nerves in patients with severe heart failure. These findings suggest that abnormally increased postinjury sympathetic nerve density may be in part responsible for the occurrence of ventricular arrhythmia and sudden cardiac death in these patients.

Topics & Keywords

Cardiac electrophysiology and arrhythmias Ion channel regulation and function Cardiac Arrhythmias and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 101, Issue 16, pp. 1960-1969

DOI: 10.1161/01.cir.101.16.1960

Field-Weighted Citation Impact: 3.78