Antitumor effect of therapeutic HPV DNA vaccines with chitosan-based nanodelivery systems

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Authors

Alireza Tahamtan · Golestan University

Amir Ghaemi · Sarem Cell Research Center

Ali Gorji · Sarem Cell Research Center

Hamid R. Kalhor · Sharif University of Technology

Azadeh Sajadian · Sarem Cell Research Center

Alijan Tabarraei · Golestan University

Abdolvahab Moradi ·

Abstract

The strong therapeutic effect induced by the Chitosan-based nanodelivery suggest that nanoparticles may be an efficient carrier to improve the immunogenicity of DNA vaccination upon intramuscular administration and the platform could be further exploited as a potential cancer vaccine candidate in humans.

Topics & Keywords

Immunotherapy and Immune Responses Cervical Cancer and HPV Research Virus-based gene therapy research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Biomedical Science

Volume 21, Issue 1, pp. 69-69

DOI: 10.1186/s12929-014-0069-z

Field-Weighted Citation Impact: 2.93