Biosensing by luminogens with aggregation-induced emission characteristics

20141,279 citationsReview

Authors

Ryan T. K. Kwok · Hong Kong University of Science and Technology

Chris Wai Tung Leung · Hong Kong University of Science and Technology

Jacky W. Y. Lam · Hong Kong University of Science and Technology

Ben Zhong Tang · Hong Kong University of Science and Technology

Abstract

Fluorescent biosensors are powerful analytical tools for studying biological events in living systems. Luminescent materials with aggregation-induced emission (AIE) attributes have attracted much research interest and have been identified as a novel class of luminogens to develop fluorescent turn-on biosensors with superior sensitivity. In this Tutorial Review, we present an overview of the AIE phenomenon and its mechanism. We summarize the structural design and working principle of AIE biosensors developed recently. Typical examples of AIE biosensors are presented.

Topics & Keywords

Luminescence and Fluorescent Materials Advanced biosensing and bioanalysis techniques Nanoplatforms for cancer theranostics

Publication Details

Published in: Chemical Society Reviews

Volume 44, Issue 13, pp. 4228-4238

DOI: 10.1039/c4cs00325j

Field-Weighted Citation Impact: 45.35

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Biosensing by luminogens with aggregation-induced emission characteristics

Authors

Abstract

Topics & Keywords

Publication Details