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B-Cell Clones as Early Markers for Chronic Lymphocytic Leukemia

2009363 citationsJournal Articlebronze Open Access

Authors

Ola Landgren · National Cancer Institute

Maher Albitar · Quest Diagnostics (United States)

Wanlong Ma · Quest Diagnostics (United States)

Fatima Abbasi · Center for Biologics Evaluation and Research

Richard B. Hayes · National Institutes of Health

Paolo Ghia · IRCCS Ospedale San Raffaele

Gerald E. Marti

Abstract

In peripheral blood obtained up to 77 months before a CLL diagnosis, prediagnostic B-cell clones were present in 44 of 45 patients with CLL.

Topics & Keywords

Chronic Lymphocytic Leukemia Research Lymphoma Diagnosis and Treatment Immunodeficiency and Autoimmune Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 360, Issue 7, pp. 659-667

DOI: 10.1056/nejmoa0806122

Field-Weighted Citation Impact: 18.05

B-Cell Clones as Early Markers for Chronic Lymphocytic Leukemia | Researchclopedia

· Center for Biologics Evaluation and Research

Neil E. Caporaso · National Institutes of Health