<i>SF3B1</i> and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

20111,060 citationsJournal Articlebronze Open Access

Authors

Lili Wang · Dana-Farber Cancer Institute

Michael S. Lawrence · Broad Institute

Youzhong Wan · Dana-Farber Cancer Institute

Petar Stojanov · Broad Institute

Carrie Sougnez · Broad Institute

Kristen Stevenson · Dana-Farber Cancer Institute

Lillian Werner ·

Abstract

Our study defines the landscape of somatic mutations in chronic lymphocytic leukemia and highlights pre-mRNA splicing as a critical cellular process contributing to chronic lymphocytic leukemia.

Topics & Keywords

Chronic Lymphocytic Leukemia Research Cancer-related Molecular Pathways Galectins and Cancer Biology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 365, Issue 26, pp. 2497-2506

DOI: 10.1056/nejmoa1109016

Field-Weighted Citation Impact: 55.16