Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

2009575 citationsJournal Articlegold Open Access

Authors

Simon G. Gregory · Duke Medical Center

Jessica J. Connelly · Center for Human Genetics

Aaron J. Towers · Center for Human Genetics

Jessica Johnson · Center for Human Genetics

Dhani Biscocho · Center for Human Genetics

Christina A. Markunas · Center for Human Genetics

Carla Lintas

Abstract

Together, these data provide further evidence for the role of OXTR and the oxytocin signaling pathway in the etiology of autism and, for the first time, implicate the epigenetic regulation of OXTR in the development of the disorder.See the related commentary by Gurrieri and Neri: http://www.biomedcentral.com/1741-7015/7/63.

Topics & Keywords

Neuroendocrine regulation and behavior Child Development and Digital Technology Autism Spectrum Disorder Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Medicine

Volume 7, Issue 1, pp. 62-62

DOI: 10.1186/1741-7015-7-62

Field-Weighted Citation Impact: 36.73