MotifMap: integrative genome-wide maps of regulatory motif sites for model species

2011188 citationsJournal Articlegold Open Access

Authors

Kenneth Daily · University of California, Irvine

Vishal R. Patel · University of California, Irvine

Paul Rigor · University of California, Irvine

Xiaohui Xie · University of California, Irvine

Pierre Baldi · University of California, Irvine

Abstract

MotifMap and its integration with other data provide a foundation for analyzing gene regulation on a genome-wide scale, and for automatically generating regulatory pathways and hypotheses. The power of this approach is demonstrated and discussed using the P53 apoptotic pathway and the Gli hedgehog pathways as examples.

Topics & Keywords

Genomics and Chromatin Dynamics Genomics and Phylogenetic Studies Gene expression and cancer classification

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: BMC Bioinformatics

Volume 12, Issue 1, pp. 495-495

DOI: 10.1186/1471-2105-12-495

Field-Weighted Citation Impact: 2.00