Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress

20053,092 citationsJournal Articlebronze Open Access

Authors

Ilan S. Wittstein · Johns Hopkins University

David R. Thiemann · Johns Hopkins University

João A.C. Lima

Kenneth L. Baughman · Brigham and Women's Hospital

Trinity J. Bivalacqua · Johns Hopkins Medicine

Abstract

Emotional stress can precipitate severe, reversible left ventricular dysfunction in patients without coronary disease. Exaggerated sympathetic stimulation is probably central to the cause of this syndrome.

Topics & Keywords

Takotsubo Cardiomyopathy and Associated Phenomena Cardiac Imaging and Diagnostics Cardiac Structural Anomalies and Repair

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 352, Issue 6, pp. 539-548

DOI: 10.1056/nejmoa043046

Field-Weighted Citation Impact: 109.00