Dopamine Increases the Efficacy of Anticancer Drugs in Breast and Colon Cancer Preclinical Models

2008168 citationsJournal Articlebronze Open Access

Authors

Debanjan Chakroborty · Biogen (Switzerland)

Uttio Roy Chowdhury · Biogen (Switzerland)

Sujit Basu · Chittaranjan National Cancer Institute

Abstract

Our study shows that dopamine significantly enhances the efficacies of commonly used anticancer drugs and also indicates that an inexpensive drug like dopamine, which is being extensively used in the clinics, might have a role as an antiangiogenic agent for the treatment of breast and colon cancer.

Topics & Keywords

Cancer, Stress, Anesthesia, and Immune Response Cancer Cells and Metastasis Cancer, Hypoxia, and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 14, Issue 8, pp. 2502-2510

DOI: 10.1158/1078-0432.ccr-07-1778

Field-Weighted Citation Impact: 2.42