Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction

2011303 citationsReviewgreen Open Access

Authors

Christopher J. O’Donnell · Framingham Heart Study

Maryam Kavousi

Albert V. Smith · Smith Family

Abstract

SNPs in the 9p21 and PHACTR1 gene loci were strongly associated with CAC and MI, and there are suggestive associations with both CAC and MI of SNPs in additional loci. Multiple genetic loci are associated with development of both underlying coronary atherosclerosis and clinical events.

Topics & Keywords

Galectins and Cancer Biology Genetic Associations and Epidemiology Connective tissue disorders research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 124, Issue 25, pp. 2855-2864

DOI: 10.1161/circulationaha.110.974899

Field-Weighted Citation Impact: 8.66