A study of quality measures for protein threading models

2001220 citationsJournal Articlegold Open Access

Authors

Adam Zemła · Lawrence Livermore National Laboratory

Daniel Fischer · Ben-Gurion University of the Negev

Leszek Rychlewski · International Institute of Molecular and Cell Biology

Abstract

We show that given a sufficient number of targets the manual and automatic measures would have given almost identical results at CASP3. If the intent is to reproduce the type of scoring done by the manual assessor in in CASP3, the best approach might be to use a combination of alignment independent and alignment dependent measures, as used in several recent studies.

Topics & Keywords

Protein Structure and Dynamics Microbial Metabolic Engineering and Bioproduction Machine Learning in Bioinformatics

Publication Details

Published in: BMC Bioinformatics

Volume 2, Issue 1, pp. 5-5

DOI: 10.1186/1471-2105-2-5

Field-Weighted Citation Impact: 2.66

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A study of quality measures for protein threading models

Authors

Abstract

Topics & Keywords

Publication Details