Enhanced Hypoprothrombinemia with Warfarin Due to Azithromycin

200419 citationsJournal Article

Authors

Krishnamoorthy B Rao · University Hospitals of Cleveland

Muralidhar Pallaki · Case Western Reserve University

Sandra R. Tolbert · Case Western Reserve University

Thomas Hornick · Louis Stokes Cleveland VA Medical Center

Abstract

Azithromycin may interact with warfarin and enhance its hypoprothrombinemic effects. This effect may be delayed for 4-8 days after a course of azithromycin has been completed. Periodic monitoring of the prothrombin time is recommended when using azithromycin in patients taking warfarin.

Topics & Keywords

Pharmacovigilance and Adverse Drug Reactions Pharmacogenetics and Drug Metabolism Atrial Fibrillation Management and Outcomes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Pharmacotherapy

Volume 38, Issue 6, pp. 982-985

DOI: 10.1345/aph.1d489

Field-Weighted Citation Impact: 0.77