Clinical Characteristics of Individuals With Germline Mutations in BRCA1 and BRCA2: Analysis of 10,000 Individuals

2002826 citationsJournal Article

Authors

Abstract

Specific features of personal and family history can be used to assess the likelihood of identifying a mutation in BRCA1 or BRCA2 in individuals tested in a clinical setting.

Topics & Keywords

BRCA gene mutations in cancer Genomic variations and chromosomal abnormalities Genetic factors in colorectal cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 20, Issue 6, pp. 1480-1490

DOI: 10.1200/jco.20.6.1480

Field-Weighted Citation Impact: 21.99