Germline <i>BAP1</i> mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers

This study reports a novel hereditary cancer syndrome caused by a germline BAP1 mutation that predisposes patients to UM, lung carcinoma, meningioma, and possibly other cancers. The results indicate that BAP1 is the candidate gene in only a small subset of hereditary UM, suggesting the contribution of other candidate genes.