Colorectal-Cancer Incidence and Mortality with Screening Flexible Sigmoidoscopy

20121,021 citationsJournal Articlebronze Open Access

Authors

Robert E. Schoen · University of Pittsburgh

Paul F. Pinsky · National Cancer Institute

Joel L. Weissfeld · University of Pittsburgh

Lance Yokochi · Pacific Health Research and Education Institute

Timothy R. Church · University of Minnesota

Adeyinka O. Laiyemo · Howard University

Robert S. Bresalier

Abstract

Screening with flexible sigmoidoscopy was associated with a significant decrease in colorectal-cancer incidence (in both the distal and proximal colon) and mortality (distal colon only). (Funded by the National Cancer Institute; PLCO ClinicalTrials.gov number, NCT00002540.).

Topics & Keywords

Colorectal Cancer Screening and Detection Genetic factors in colorectal cancer Gastric Cancer Management and Outcomes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 366, Issue 25, pp. 2345-2357

DOI: 10.1056/nejmoa1114635

Field-Weighted Citation Impact: 53.97