Potential Applications for Circulating Tumor Cells Expressing the Insulin-Like Growth Factor-I Receptor

2007193 citationsJournal Articlebronze Open Access

Authors

Johann S. de Bono · Royal Marsden NHS Foundation Trust

Gerhardt Attard · Royal Marsden NHS Foundation Trust

Alex A. Adjei · Mayo Clinic

Michaël Pollak · McGill University

Peter C.C. Fong · Royal Marsden NHS Foundation Trust

Paul Haluska · Mayo Clinic

Luisa Roberts ·

Abstract

IGF-IR expression is detectable by immunofluorescence on CTCs. These data support the further evaluation of CTCs in pharmacodynamic studies and patient selection, particularly in advanced prostate cancer.

Topics & Keywords

Growth Hormone and Insulin-like Growth Factors Cancer Cells and Metastasis Cancer, Hypoxia, and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 13, Issue 12, pp. 3611-3616

DOI: 10.1158/1078-0432.ccr-07-0268

Field-Weighted Citation Impact: 11.53