Two New Modes of Pd-Catalyzed Domino-Tetracyclization of Bromodienynes—5-exo-trig Cyclization Wins overβ-Hydride Elimination

199967 citationsJournal Article

Authors

Stefan Schweizer · University of Göttingen

Zhi-Zhong Song · University of Göttingen

Philip J. Parsons · University of Sussex

Armin de Meijere · University of Göttingen

Abstract

Remarkable increases of molecular complexity in a single procedural step are achieved with the title reaction. Only a slight modification in the substitution pattern on the acyclic precursor 2 can change the mode of tetracyclization to either yield skeletons of type 1 or 3 exclusively.

Topics & Keywords

Catalytic Alkyne Reactions Catalytic C–H Functionalization Methods Asymmetric Hydrogenation and Catalysis

Publication Details

Published in: Angewandte Chemie International Edition

Volume 38, Issue 10, pp. 1452-1454

DOI: 10.1002/(sici)1521-3773(19990517)38:10<1452::aid-anie1452>3.0.co;2-p

Field-Weighted Citation Impact: 1.97

Command Palette

Two New Modes of Pd-Catalyzed Domino-Tetracyclization of Bromodienynes—5-exo-trig Cyclization Wins overβ-Hydride Elimination

Authors

Abstract

Topics & Keywords

Publication Details