Helicase–Primase Inhibitor Pritelivir for HSV-2 Infection

2014160 citationsJournal Article

Authors

Anna Wald · University of Washington

Lawrence Corey · University of Washington

Burkhard Timmler · AiCuris (Germany)

Amalia Magaret · Fred Hutch Cancer Center

Terri Warren · Westover Heights Clinic

Stephen K. Tyring

Christine Johnston · Fred Hutch Cancer Center

Abstract

Pritelivir reduced the rates of genital HSV shedding and days with lesions in a dose-dependent manner in otherwise healthy men and women with genital herpes. (Funded by AiCuris; ClinicalTrials.gov number, NCT01047540.).

Topics & Keywords

Herpesvirus Infections and Treatments Animal Virus Infections Studies Virus-based gene therapy research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 370, Issue 3, pp. 201-210

DOI: 10.1056/nejmoa1301150

Field-Weighted Citation Impact: 11.59