A Variant in <i>LDLR</i> Is Associated With Abdominal Aortic Aneurysm

201395 citationsReviewbronze Open Access

Authors

Declan Bradley

Anne E. Hughes · Jensen Hughes (United States)

Stephen A. Badger

Gregory T. Jones · St. Gregory's University

Sólveig Grétarsdóttir

K G Burnand

Anne H. Child

Abstract

LDLR rs6511720 is associated with AAA. This finding is consistent with established effects of this variant on coronary artery disease. Shared causal pathways with other cardiovascular diseases may present novel opportunities for preventative and therapeutic strategies for AAA.

Topics & Keywords

Aortic aneurysm repair treatments Aortic Disease and Treatment Approaches Retirement, Disability, and Employment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation Cardiovascular Genetics

Volume 6, Issue 5, pp. 498-504

DOI: 10.1161/circgenetics.113.000165

Field-Weighted Citation Impact: 7.13