Cortical Brain Development in Nonpsychotic Siblings of Patients With Childhood-Onset Schizophrenia

2007162 citationsJournal Article

Authors

Nitin Gogtay · National Institute of Mental Health

Deanna Greenstein

Abstract

Prefrontal and temporal GM loss in COS appears to be a familial/trait marker. Amelioration of regional GM deficits in healthy siblings was associated with higher global functioning (GAS scores), suggesting a relationship between brain plasticity and functional outcome for these nonpsychotic, nonspectrum siblings.

Topics & Keywords

Functional Brain Connectivity Studies Schizophrenia research and treatment Advanced Neuroimaging Techniques and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Archives of General Psychiatry

Volume 64, Issue 7, pp. 772-772

DOI: 10.1001/archpsyc.64.7.772

Field-Weighted Citation Impact: 5.05