Increased Epidermal Growth Factor Receptor Gene Copy Number Is Associated With Poor Prognosis in Head and Neck Squamous Cell Carcinomas

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Authors

Christine H. Chung · University of Colorado Cancer Center

Kim Ely · University of Colorado Cancer Center

Loris McGavran · University of Colorado Cancer Center

Marileila Varella‐Garcia · University of Colorado Cancer Center

Joel S. Parker · University of Colorado Cancer Center

Natalie B. Parker · University of Colorado Cancer Center

Carolyn Jarrett

Abstract

High EGFR gene copy number by FISH is frequent in HNSCC and is a poor prognostic indicator. Additional investigation is indicated to determine the biologic significance and implications for EGFR inhibitor therapies in HNSCC.

Topics & Keywords

Lung Cancer Treatments and Mutations Cholangiocarcinoma and Gallbladder Cancer Studies Head and Neck Cancer Studies

Publication Details

Published in: Journal of Clinical Oncology

Volume 24, Issue 25, pp. 4170-4176

DOI: 10.1200/jco.2006.07.2587

Field-Weighted Citation Impact: 25.17

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Increased Epidermal Growth Factor Receptor Gene Copy Number Is Associated With Poor Prognosis in Head and Neck Squamous Cell Carcinomas

Authors

Abstract

Topics & Keywords

Publication Details